Intensive one-week course from Monday to Friday. Lectures and hands-on laboratory courses will be provided by local and invited lecturers from academia and industry.
As scientists and wider society have become increasingly aware of the negative impacts of global warming and climate change, the need to refine and develop processes that are sustainable and environmentally friendly has become an ever-pressing issue. As such, it is some cause for consternation that catalyzing chemical reactions often involves catalysts that are toxic and contain chemical residues that can pollute the environment. In addition, chemical catalysis can be a laborious and costly exercise. It is for these reasons that researchers around the world are focusing on developing a new means of catalyzing chemical reactions that is more efficient and environmentally friendly.
99% of all microorganism cannot be cultivated and thus are not easily accessible for biotechnology. Metagenomics is a key technology to explore the not-yet-cultivated microbes for bioindustries. Since the onset of metagenomics 20 years ago, numerous novel biocatalysts and other valuable biomolecules have been mined from diverse metagenomes. While modern sequencing technologies have given us fast and reliable insight into the genomes of complex microbial communities, mining, expressing proteins, and delivering them to bioindustries is still a major challenge and often takes several years.
The course will summarize current knowledge in the field of functional and applied metagenomics. It will point out bottlenecks and challenges in the field of enzyme mining, and it will give insights into to novel technology developments using functional and in silico mining.
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- Mining the soil metagenome
- Mining the sea
- Metagenome enzyme biotechnology
- Structures and functions from metagenomes
- Upscaling and industrial applications
- DNA isolation, amplification, and cell-free expression
- Insights into complex biofilm metagenomes
- Garo Antranikian (TU Hamburg, Germany)
- Don Cowan (University of Pretoria, South Africa)
- Rolf Daniel (University of Göttingen, Germany)
- Manuel Ferrer (CSIC, Madrid, Spain)
- Ute Hentschel Humeida (Geomar, Kiel, Germany)
- Karl-Erich Jäger (University of Düsseldorf, Germany)
- Rainhard Koch (Bayer, Leverkusen, Germany)
- Stephan Kolkenbrock (Altona Diagnostics, Germany)
- Andreas Liese (TU Hamburg, Germany)
- Jürgen Pleiss (University of Stuttgart, Germany)
- Matthias Rarey (University of Hamburg, Germany)
- Ruth Schmitz-Streit (University of Kiel, Germany)
- Björn Voß (University of Stuttgart, Germany)
- Alexander Wentzel (SINTEF, Trondheim, Norway)